Peraza AA, Li W, Lele A, Lazureanu DG, Hampton MF, Do RM, Lafrades MC, Barajas MG, Batres AA,McNally FJ. Inward transport of organelles drives outward migration of the spindle during C. elegans meiosis. bioRxiv 2024.09.19.613972; doi: https://doi.org/10.1101/2024.09.19.613972.
Gong T, McNally KP, Konanoor S, Peraza A, Bailey C, Redemann S, McNally FJ. Roles of Tubulin Concentration during Prometaphase and Ran-GTP during Anaphase of Caenorhabditis elegans Meiosis. Life science alliance. 2024. 7(9), e202402884.
Magadum MM, McNally FJ. DLGR-1, a homolog of vertebrate DLGAP proteins, regulates spindle length and anaphase velocity during C. elegans meiosis. MicroPubl Biol. 2024;2024:10.17912/micropub.biology.001305. doi:10.17912/micropub.biology.001305
Beath E, Bailey C, Magadum MM, Qiu S, McNally KP, McNally FJ. Katanin, kinesin-13 and ataxin-2 inhibit premature interaction between maternal and paternal genomes in C. elegans zygotes. eLife 13:RP97812
McNally KP, McNally FJ. Auxin-induced degradation of the aurora A kinase, AIR-1, in C. elegans does not prevent assembly of bipolar meiotic spindles. MicroPubl Biol. 2024. doi: 10.17912/micropub.biology.001123. PMID: 38362120; PMCID: PMC10867633.
Li W, Crellin HA, Cheerambathur D, McNally FJ. Redundant microtubule crosslinkers prevent meiotic spindle bending to ensure diploid offspring in C. elegans. PLoS Genet. 2023 Dec 27;19(12):e1011090. doi: 10.1371/journal.pgen.1011090. PMID: 38150489.
Gong T, McNally FJ. Caenorhabditis elegans spermatocytes can segregate achiasmate homologous chromosomes apart at higher than random frequency during meiosis I. Genetics. 2023 Apr 6;223(4):iyad021. doi: 10.1093/genetics/iyad021. PMID: 36792551.
McNally KP, Beath EA, Danlasky BM, Barroso C, Gong T, Li W, Martinez-Perez E, McNally FJ. Cohesin is required for meiotic spindle assembly independent of its role in cohesion in C. elegans. PLoS Genet. 2022 Oct 24;18(10):e1010136. doi: 10.1371/journal.pgen.1010136. PMID: 36279281; PMCID: PMC9632809.
Juanico IY, Meyer CM, McCarthy JE, Gong T, McNally FJ. Paternal mitochondria from an rmd-2, rmd-3, rmd-6 triple mutant are properly positioned in the C. elegans zygote. MicroPubl Biol. 2021 Jul 19;2021:10.17912/micropub.biology.000422. doi: 10.17912/micropub.biology.000422. PMID: 34296068; PMCID: PMC8290264.
Danlasky BM, Panzica MT, McNally KP, Vargas E, Bailey C, Li W, Gong T, Fishman ES, Jiang X, McNally FJ. Evidence for anaphase pulling forces during C. elegans meiosis. J Cell Biol. 2020 Dec 7;219(12):e202005179. doi: 10.1083/jcb.202005179.PMID: 33064834
Lombino FL, Muhia M, Lopez-Rojas J, Brill MS, Thies E, Ruschkies L, Lutz D, Richter M, Hausrat TJ, Lopes AT, McNally FJ, Hermans-Borgmeyer I, Dunleavy JEM, Hoffmeister-Ullerich S, Frotscher M, Misgeld T, Kreutz MR, de Anda FC, Kneussel M.Sci Rep.The Microtubule Severing Protein Katanin Regulates Proliferation of Neuronal Progenitors in Embryonic and Adult Neurogenesis. 2019 Nov 4;9(1):15940. doi: 10.1038/s41598-019-52367-3.PMID: 31685876
Vargas E, McNally KP, Cortes DB, Panzica MT, Danlasky BM, Li Q, Maddox AS, McNally FJ.Spherical spindle shape promotes perpendicular cortical orientation by preventing isometric cortical pulling on both spindle poles during C. elegans female meiosis.Development. 2019 Oct 21;146(20):dev178863. doi: 10.1242/dev.178863.PMID: 31575646
McNally FJ, Roll-Mecak Microtubule-severing enzymes: From cellular functions to molecular mechanism. A.J Cell Biol. 2018 Dec 3;217(12):4057-4069. doi: 10.1083/jcb.201612104. Epub 2018 Oct 29.PMID: 30373906
Nithianantham S, McNally FJ, Al-Bassam Structural basis for disassembly of katanin heterododecamers. J.J Biol Chem. 2018 Jul 6;293(27):10590-10605. doi: 10.1074/jbc.RA117.001215. Epub 2018 May 11.PMID: 29752405 Free PMC article.
Panzica MT, McNally FJ. 2018. Mechanisms that prevent catastrophic interactions between paternal chromosomes and the oocyte meiotic spindle. Cell Cycle. 17(5):529-534.
McNally FJ. 2017. Competing chromosomes explain junk DNA. Science. 358(6363):594-595.
Vargas E, McNally K, Friedman JA, Cortes DB, Wang DY, Korf IF, McNally FJ. 2017. Autosomal trisomy and triploidy are corrected during female meiosis in Caenorhabditis elegans. Genetics. 207(3):911-922.
Flynn JR, McNally FJ. 2017. A casein kinase 1 prevents expulsion of the oocyte meiotic spindle into a polar body by regulating cortical contractility. Mol Biol Cell. 28(18):2410-2419.
Panzica MT, Marin HC, Reymann AC, McNally FJ. 2017. F-actin prevents interaction between sperm DNA and the oocyte meiotic spindle in C. elegans. J Cell Biol. 216(8):2273-2282.
McNally KP, Panzica MT, Kim T, Cortes DB, McNally FJ. 2016. A novel chromosome segregation mechanism during female meiosis. Mol Biol Cell. 27(16):2576-89.
Crowder ME, Flynn JR, McNally KP, Cortes DB, Price KL, Kuehnert PA, Panzica MT, Andaya A, Leary JA, McNally FJ. 2015. Dynactin-dependent cortical dynein and spherical spindle shape correlate temporally with meiotic spindle rotation in Caenorhabditis elegans. Mol Biol Cell. 26(17):3030-46.
Cortes DB, McNally KL, Mains PE, McNally FJ. 2015. The asymmetry of female meiosis reduces the frequency of inheritance of unpaired chromosomes. Elife.4:e06056.
McNally K, Berg E, Cortes DB, Hernandez V, Mains PE, McNally FJ. 2014. Katanin maintains meiotic metaphase chromosome alignment and spindle structure in vivo and has multiple effects on microtubules in vitro. Mol Biol Cell. 25(7):1037-49.
McNally, F.J. 2013. Mechanisms of spindle positioning. J Cell Biol. 200(2):131-40.
O’Donnell, L., Rhodes, D., Smith, S.J., Merriner, D.J., Clark, B.J., Borg, C., Whittle, B., O’Connor, A.E., Smith, L.B., McNally, F.J., de Kretser, D.M., Goodnow, C.C., Ormandy, C.J., Jamsai, D., O’Bryan, M.K. 2012. An essential role for katanin p80 and microtubule severing in male gamete production. PLoS Genet. 8(5)e1002698.
McNally, K.L., Fabritius, A.S., Ellefson, M.L., Flynn, J.R., Milan, J.A., McNally., F.J. 2012. Kinesin-1 prevents capture of the oocyte meiotic spindle by the sperm aster. Dev Cell. 22(4):788-98.
Loughlin, R., Wilbur, J.D., McNally, F.J., Nédélec and Heald, R. 2011. Katanin contributes to interspecies spindle length scaling in Xenopus. Cell. 147:1397-1407.
Fabritius, A.S., Flynn, J.R. and McNally, F.J. 2011. Initial diameter of the polar body contractile ring is minimized by the centralspindlin complex. Dev Biol. 359(1):137-148.
Ellefson, M.L. and McNally, F.J. 2011. CDK-1 inhibits meiotic spindle shortening and dynein-dependent spindle rotation in C. elegans. J. Cell Biol. 193(7):1229-44.
McNally, K.L. and McNally, F.J. 2011. The spindle assembly function of Caenorhabditis elegans katanin does not require microtubule-severing activity. Mol. Biol. Cell. 22: 1550-1560.
Fabritius, A.S., Ellefson, M.L., and McNally, F.J. 2010. Nuclear and spindle positioning in oocyte meiosis. Curr Opin Cell Biol. 23: 78-84.
McNally, K.L., Martin, J.L., Ellefson, M., McNally, F.J. 2010. Kinesin-dependent transport results in polarized migration of the nucleus in oocytes and inward movement of yolk granules in meiotic embryos. Dev. Biol. 339:126-140.
Roll-Mecak, A., McNally, F.J. 2010. Microtubule-severing enzymes. Curr Opin Cell Biol. 22:96-103.
Meyerzon, M., Fridolfsson, H.N., Ly, N., McNally, F.J., and Starr, D.A. 2009. UNC-83 is a nuclear-specific cargo adaptor for kinesin-1-mediated nuclear migration. Development. 136: 2725-2733.
Johnson, J.L., Lu, C., Raharjo, E., McNally, K., McNally, F.J., and Mains, P.E. 2009. Levels of the ubiquitin ligase substrate adaptor MEL-26 are inversely correlated with MEI-1/katanin microtubule-severing activity during both meiosis and mitosis. Dev. Biol. 330: 349-357.
Ellefson, M.L., and McNally, F.J. 2009. Kinesin-1 and cytoplasmic dynein act sequentially to move the meiotic spindle to the oocyte cortex in Caenorhabditis elegans. Mol. Biol. Cell. 20: 2722-2730.
McNally, K., Audhya, A., Oegema, K., and F.J. McNally. 2006. Katanin controls mitotic and meiotic spindle length. J. Cell Biol. 175: 881-891.
McNally, K.L., and F.J. McNally. 2005. Fertilization initiates the transition from anaphase I to metaphase II during C. elegans meiosis. Dev. Biol. 282: 218-230.
Yang, H., Mains, P.E., and F.J. McNally. 2005. Kinesin-1 mediates translocation of the meiotic spindle to the oocyte cortex through KCA-1, a novel cargo adapter. J. Cell Biol. 169: 447-457.
McNally, F. 2003. Microtubule dynamics: New surprises from an old MAP. Current Biol. 13: R597-R599
Yang, H., McNally, K., and F.J. McNally. 2003. MEI-1/katanin is required for translocation of the meiosis I spindle to the oocyte cortex in C. elegans. Dev. Biol. 260: 245-259.
McNally, K.P., Buster, D. and F.J. McNally. 2002. Katanin-mediated microtubule severing can be regulated by multiple mechanisms. Cell Motil. Cytoskel. 53: 337-349.
Buster, D.W., McNally, K., and F.J. McNally. 2002. Katanin inhibition prevents the redistribution of g-tubulin at mitosis. J. Cell Science 115: 1083-1092.
McNally, F.J. 2001. CLASPing the end to the edge. Current Biology 11: R477-R480.
Srayko, M., Buster, D.W., Bazirgan, O.A., McNally, F.J. and P.E. Mains. 2000. MEI-1/MEI-2 katanin-like microtubule severing activity is required for C. elegans meiosis. Genes and Development. 14: 1072-108.
McNally, K.P., Bazirgan, O.A., and F.J. McNally. (2000). Two domains of p80 katanin regulate microtubule severing and spindle pole targeting by p60 katanin. J. Cell Science. 113: 1623-1633.
McNally, F. 2000. Capturing a ring of samurai. Nature Cell Biol. 2: E4-E7.
McNally, F.J. 1999. Katanin. pp 264-265 in Guidebook to the Cytoskeletal and Motor Proteins. Oxford University Press. T. Kreis and R. Vale eds.
McNally, F.J. (1999). Microtubule dynamics: Controlling split ends. Current Biology 9: 274-276.
Ahmad, F.J., Yu, W., McNally, F.J. and P.W. Baas. (1999). An essential role for katanin in severing microtubules in the neuron. J. Cell Biol. 145: 305-315.
McNally, F.J., and S. Thomas. (1998). Katanin is responsible for the M-phase microtubule-severing activity in Xenopus eggs. Mol. Biol. Cell. 9: 1847-1861.
Hartman, J.J., Mahr, J., McNally, K., Okawa, K., Iwamatsu, A., Thomas, S., Cheesman, S., Heuser, J., Vale, R.D. and F.J. McNally. 1998. Katanin, a microtubule severing protein, is a novel AAA ATPase that targets to the centrosome using a WD40 domain. Cell 93: 277-287.
Lohret, T.A., McNally, F.J., and L.M. Quarmby. 1998. A role for katanin-mediated axonemal severing during Chlamydomonas deflagellation. Mol. Biol. Cell 9: 1195-1207.
McNally, F. J. 1998. Purification and Assay of the Microtubule-Severing Protein, Katanin. Methods in Enzymology 298: 206-218.
McNally, F.J., Okawa, K., Iwamatsu, A., and R.D. Vale. 1996. Katanin, the microtubule-severing ATPase, is concentrated at centrosomes. J. Cell Sci. 109: 561-567.
McNally, F.J. 1996. Modulation of microtubule dynamics during the cell cycle. Curr. Opin. Cell Biol. 8: 23-29.
McNally, F. and R. Vale. 1993. Identification of Katanin, an ATPase that Severs and Disassembles Stable Microtubules. Cell 75: 419-429.